Principal Investigator

Principal Investigator -Clinical ResearchRelocation Assistance AvailableFull-Time | On-Site

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About the OpportunityAn established global clinical research organization is seeking an experienced physician to serve as the lead and sole Principal Investigator for its Springfield, Missouri research operation.
This is not a traditional study-level PI position. The physician will hold meaningful authority across the clinical research portfolio, leading their own trials while providing senior medical oversight, guiding research teams, and supporting additional PRN and contract investigators.
This is an opportunity to become the primary clinical leader within a sophisticated research environment and directly influence how trials are conducted.
Why Consider This Opportunity?Serve as the sole, senior Principal Investigator for the research operationEstablished clinical research program with decades of experienceBroad exposure to Phase I-IV clinical trialsOpportunity to mentor research staff and support other investigatorsHigh level of autonomy and physician leadershipCollaboration with leading pharmaceutical and biotechnology sponsorsOperate with meaningful autonomy within an established global organizationStrong long-term career growth potentialRelocation support available for qualified candidates
Key ResponsibilitiesServe as Principal Investigator for early-phase industry-sponsored clinical trialsEnsure studies are conducted in accordance with ICH-GCP guidelines and protocol requirementsOversee participant safety, informed consent, and study conductReview eligibility criteria and perform medical assessmentsEvaluate adverse events and ongoing participant safetyCollaborate with sponsors, IRBs, monitors, and xzbcwsv auditorsProvide leadership and mentorship to clinical research staffSupport overall study quality, regulatory compliance, and data integrity
QualificationsMD or DOBoard Certified or Board Eligible (preferred but not required)Strong knowledge of ICH-GCP and clinical research regulationsExperience in Endocrinology, Diabetes, Obesity, Metabolic Disease, Thyroid Disease, Internal Medicine, or related therapeutic areas preferredStrong interest in clinical researchIf you are interested in learning more about this opportunity, please apply directly for a confidential discussion.