Scientist/Sr Scientist, DEL Selection

New Haven, CT | On-Site
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Our client, a Venture-backed biotechnology company developing next-generation small molecule therapeutics is seeking a Scientist, DEL Selections to lead and execute DNA-Encoded Library (DEL) screening campaigns supporting drug discovery programs. This is a highly visible, hands-on role partnering with biology, chemistry, and computational teams to identify and validate novel small molecule hits and advance programs from hit discovery through lead optimization.Key ResponsibilitiesDesign and execute DEL selection campaigns and protein capture assaysBuild and maintain internal DEL screening capabilities, from assay setup through NGS sample preparationCollaborate cross-functionally to develop data-driven screening strategiesAnalyze and interpret DEL datasets to drive hit identification and validationPresent scientific findings and recommendations to project teams and leadershipSupport compound characterization through biophysical and biochemical assays (e.g., SPR, TR-FRET)QualificationsPhD with postdoctoral training and 3-5+ years of industry experience, or BS/MS with significant relevant xzbcwsv experienceDeep expertise in DNA-Encoded Library (DEL) screening, sample preparation, and data analysisProven ability to independently drive multiple drug discovery campaignsStrong understanding of hit identification and validation workflowsExperience with biophysical assay platforms is a plusAbility to thrive in a fast-paced, collaborative biotech environment